The Science Behind
NMN (nicotinamide mononucleotide) has an indirect role in the survival of every one of our cells. To understand this role, we first need to take a few steps back.
Everything happening in any life form, like breathing, moving and even thinking is based on biochemical reactions. Every biochemical reaction requires energy. Our bodies take this energy from food and mitochondria convert it into the currency that every cell can use. A protagonist in energy production is a molecule called NAD (Nicotinamide Adenine Dinucleotide). NAD is found in two forms: NAD+ (oxidized form) and NADH (reduced form). NAD is a co-enzyme, a molecule that helps other proteins and enzymes do their job. One of these jobs is producing energy in mitochondria and reducing oxidative stress.
And yet, NAD does much more than that.
Resveratrol is a guardian molecule of plants. It protects them from injury and pathogen infection. It belongs to the greater family of polyphenols, like quercetin. Our diets include small quantities of resveratrol; mainly from grapes, red wine, and knotweed. There are two main forms of resveratrol: trans and cis. Trans-resveratrol is the most abundant, stable and biologically potent form.
Did you know what is the connection between oak trees and our health? Yes, oxygen is a good answer but not the only one. Quercetin is another one. The word quercetin comes from the Latin word Quercus, which is a type of oak tree.
Quercetin is also called “the queen of flavonoids”, as it is one of the best-studied flavonoids.
TMG stands for trimethylglycine, a long name for a short molecule. As its name indicates, TMG is a glycine with three methyl groups. Glycine is an amino acid, a building block of proteins. A methyl group is one carbon atom surrounded by three hydrogens. We can synthesize our own TMG. We also receive it from our diets and especially wheat bran, wheat germ, wheat bread, spinach and beets.
Spermidine, what an intriguing name! Don’t you panic though! Spermidine may have first been detected in sperm but this is not where it is sourced from. In fact, spermidine is a ubiquitous molecule in all organisms. The richest dietary sources of spermidine are plants, especially soybean oil and wheat germ, and mushrooms. Good animal sources are seafood and liver. Even our gut flora produces small amounts of spermidine.