Pure Alpha GPC
/
Alpha GPC is a form of choline that enhances memory, cognitive function, and supports brain health.
Benefits
Benefits
- Boosts neuronal communication – this increases focus and maintains cognition as you age.
- Enhances athletic performance – Alpha GPC can increase your power output during resistance & strength workouts.
- Supports learning and high-focus work – by increasing acetylcholine levels in the brain, Alpha GPC may help you focus and sustain information better.
Dosage
Dosage
Take 1 capsule (300 mg) one hour before highly-focused work or a workout.
You may adjust the dose according to your needs.
Ingredients
Ingredients
- 300 mg of 99% pure Alpha-glycerylphosphorylcholine per serving.
- Microcrystalline cellulose capsule (safe for vegans) to contain Alpha GPC.
Also Bought Together
GET TO KNOW
What is Alpha GPC?​
Alpha GPC (Alpha-glycerophosphocholine) is a natural choline compound crucial for brain health and cognitive enhancement. It increases levels of acetylcholine, a neurotransmitter vital for memory, learning, and muscle control.Â
Think of acetylcholine as the messenger that facilitates communication between brain cells, much like a group chat sharing important updates. The more effective this communication, the better your ability to remember information, focus on tasks, and learn new concepts.

Additionally, Alpha GPC is recognized for its support of physical performance, as it promotes better muscle contractions and power output during exercise, making it a favored choice among athletes.

Enhances Cognitive Function​
As a rich source of choline, Alpha GPC serves as a precursor to acetylcholine, a neurotransmitter essential for various cognitive processes and even muscle contraction. By increasing acetylcholine levels in the brain, Alpha GPC enhances neuronal communication [1], which is vital for maintaining cognition and countering age-related cognitive decline.
Boosts Focus and Mental Clarity
Taking Alpha GPC before mentally demanding tasks can significantly enhance focus, cognition, and mental clarity. Studies suggest that users experience improved attention and motivation [2], making it particularly effective for tasks requiring sustained cognitive effort.
Supports Athletic Performance​
Research has demonstrated that Alpha GPC can increase power output during resistance training, with some studies showing improvements in performance metrics, such as vertical jump height [3] and peak bench press force [4] while also increasing growth hormone production [4] [5]. This makes it a valuable supplement for athletes looking to maximize their physical performance
Improves Memory and Learning
Alpha GPC may enhance learning abilities by increasing acetylcholine levels in the brain, a key neurotransmitter for information processing and retention [6]. Research indicates that adequate choline intake can improve cognition [7], with studies showing positive effects on learning and memory in animal models [8].

HOW TO USE PURE ALPHA-GPC
Alpha-GPC Dosage
Daily Dosage Recommendations:
A typical dose ranges from 300 to 1,200 mg per day, based on research [9] [10]. For cognitive support and focus, 300–600 mg is commonly taken about 30–60 minutes before mentally demanding tasks or exercise.
Best Practices:
Alpha GPC does not need to be taken daily and can be used as needed. It may be taken with or without food. Effects typically last 4–6 hours, helping maintain elevated choline levels during that time.
THE SCIENCE BEHIND ALPHA GPC
Pure Alpha GPC Facts
Highest Purity: partiQlar’s Pure Alpha-GPC capsules exceed 99% purity, ensuring superior quality and efficacy in every dose.
Single-Ingredient Formulation:Â supported by scientific research, Pure Alpha-GPC provides an effective 300 mg dosage of Alpha-glycerophosphocholine, ensuring maximum potency and flexibility.
Third-Party Tested:Â each batch undergoes rigorous third-party testing for purity and potency, ensuring transparency and reliability.
Sourced from a reputable and certified supplier, it is manufactured in a facility registered with the US FDA and NSF, adhering to stringent regulatory standards for safety and quality assurance.

Frequently Asked Questions About Pure Alpha GPC
Seriously, our team of supplement experts and scientists have answers
What is Alpha GPC?
What is Alpha GPC?
Alpha GPC (Alpha-glycerophosphocholine) is a natural choline compound crucial for brain health and cognition. It increases levels of acetylcholine, a neurotransmitter vital for memory, learning, and muscle control. Think of acetylcholine as the messenger that facilitates communication between brain cells, much like a group chat sharing important updates. The more effective this communication, the better your ability to remember information, focus on tasks, and learn new concepts while also reducing the effect of age-related cognitive decline.
Additionally, Alpha GPC is recognized for its support of physical performance, as it promotes better muscle contractions and power output during exercise, making it a favored choice among athletes.
How long does Alpha GPC take to work?
How long does Alpha GPC take to work?
As it easily crosses the blood-brain barrier, alpha GPC typically begins to take effect within 30 to 60 minutes after ingestion, although this can vary based on individual metabolism and dosage. Users may notice improvements in cognition and mental functions, such as enhanced focus and memory recall, within this timeframe or with longer use.Â
For athletic performance, research indicates that growth hormone secretion peaks about 30 minutes after taking Alpha GPC as a pre-workout supplement, which can support muscle building, faster recovery, and improved strength. Increased power output may become noticeable after consistent use over several days.
What is Acetylcholine and Choline?
What is Acetylcholine and Choline?
Acetylcholine is a neurotransmitter that plays a key role in communication between nerve cells. It is essential for many functions, including muscle movement, memory, cognition, and learning. Choline is a nutrient that serves as a precursor to acetylcholine, meaning that it is necessary for the body to produce this important neurotransmitter.
Is Alpha GPC a nootropic?
Is Alpha GPC a nootropic?
Yes, Alpha GPC is considered a nootropic, which refers to substances that may enhance cognition, memory, creativity, or motivation in healthy individuals​. As a choline source that increases acetylcholine levels, Alpha GPC is commonly used to improve focus and mental clarity.
Can Alpha GPC improve mood?
Can Alpha GPC improve mood?
Some studies suggest that Alpha GPC may have a positive impact on mood by enhancing acetylcholine levels and supporting neurotransmitter balance, potentially aiding in anxiety and depression management. However, more research is needed to fully establish these effects​.
How often should you take Alpha GPC?
How often should you take Alpha GPC?
You can take Alpha GPC as needed, and daily supplementation is not necessary. If you’re wondering how much Alpha GPC you should take, the typical Alpha GPC effective dose ranges from 300 to 1,200 mg per day, depending on your goals. For cognitive enhancement or athletic performance, many users find it effective to take Alpha GPC about 30 to 60 minutes before mentally demanding tasks or workouts. If you tolerate the initial dosage well, you may increase the frequency or amount based on your individual needs​.
What is the difference between Alpha GPC and CDP Choline?
What is the difference between Alpha GPC and CDP Choline?
Alpha GPC and CDP choline (cytidine diphosphate choline) are both choline sources but have different compositions and mechanisms. Alpha GPC is more bioavailable and quickly crosses the blood-brain barrier, making it effective for enhancing cognitive function and physical performance. CDP choline also supports brain health but is thought to additionally boost dopamine levels, which may aid in mood regulation.
Can Alpha GPC be taken with food?
Can Alpha GPC be taken with food?
Yes, you can take Alpha GPC with food as well as without. Some users prefer taking it with meals to minimize potential gastrointestinal discomfort. It’s advisable to start with a lower dose and see how your body reacts.
What are the side effects of Alpha-GPC?
What are the side effects of Alpha-GPC?
Alpha GPC is generally well-tolerated, but some users may experience mild side effects, such as headaches, nausea, or gastrointestinal discomfort. Other potential effects include dizziness or low blood pressure, especially in those sensitive to changes in blood pressure. Starting with a lower dose can help minimize these effects.
Always consult a healthcare professional before starting any new supplement regimen, particularly if you have underlying health conditions or are taking other medications.
What happens to Alpha GPC when exposed to moisture?
What happens to Alpha GPC when exposed to moisture?
Alpha GPC is hygroscopic, meaning it can absorb moisture from the air. If the capsules are exposed to high humidity or not stored properly, they may clump together, causing the powder to change from a solid form to a gel-like consistency.
While this doesn’t mean the product has degraded, it indicates improper storage. To maintain Alpha GPC capsule quality, store them in a cool, dry place in their original packaging.
How is PartiQlar's Pure Alpha-GPC better?
How is PartiQlar's Pure Alpha-GPC better?
PartiQlar’s Pure Alpha-GPC is formulated with the highest quality ingredients, making it one of the best Alpha-GPC supplements available. Our single-ingredient formulation guarantees maximum potency at 99%, significantly surpassing the industry standard of 50%. Each batch undergoes rigorous third-party testing to ensure purity, potency, and safety, providing a reliable and effective supplement for cognitive enhancement and athletic performance.Â
Scientific References
Scientific References
[1] Picciotto MR, Higley MJ, Mineur YS. Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 2012;76(1):116–129. doi:10.1016/j.neuron.2012.08.036. Available at: ScienceDirect
[2] Tamura Y, Takata K, Matsubara K, Kataoka Y. Alpha-glycerylphosphorylcholine increases motivation in healthy volunteers: a single-blind, randomized, placebo-controlled human study. Nutrients. 2021;13(6):2091. doi:10.3390/nu13062091. Available at: MDPI.com
[3] Marcus L, Soileau J, Judge LW, Bellar D. Evaluation of the effects of two doses of alpha glycerylphosphorylcholine on physical and psychomotor performance. Journal of the International Society of Sports Nutrition. 2017;14:39. doi:10.1186/s12970-017-0196-5. Available at: https://pubmed.ncbi.nlm.nih.gov/29042830
[4] Ziegenfuss TN, Landis J, Hofheins J, et al. Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Journal of the International Society of Sports Nutrition. 2008;5(Suppl 1):P15. doi:10.1186/1550-2783-5-S1-P15. Available at: https://jissn.biomedcentral.com/articles/10.1186/1550-2783-5-S1-P15
[5] Kawamura T, Okubo T, Sato K, et al. Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults. Nutrition. 2012;28(11–12):1122–1126. doi:10.1016/j.nut.2012.02.011. Available at: https://pubmed.ncbi.nlm.nih.gov/22673596/
[6] Yu HJ, Kim YL, Kim MJ, et al. The effect of choline alphoscerate on non-spatial memory and neuronal differentiation in a rat model of dual stress. Brain Res. 2022;1786:147900. doi:10.1016/j.brainres.2022.147900. Available at: https://www.sciencedirect.com/science/article/pii/S2324242622000985
[7] Traini E, Bramanti V, Amenta F. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline): an old choline-containing phospholipid with a still interesting profile as cognition-enhancing agent. Curr Alzheimer Res. 2013;10(10):1070–1079. doi:10.2174/15672050113106660173. Available at: https://pubmed.ncbi.nlm.nih.gov/24156263/
[8] Drago F, Mauceri F, Nardo L, et al. Behavioral effects of L-alpha-glycerylphosphorylcholine: influence on cognitive mechanisms in the rat. Pharmacol Biochem Behav. 1992;41(2):445–448. doi:10.1016/0091-3057(92)90124-X. Available at: https://pubmed.ncbi.nlm.nih.gov/1574535/
[9] Parker AG, Byars A, Purpura M, et al. The effects of alpha-glycerylphosphorylcholine, caffeine or placebo on markers of mood, cognitive function, power, speed, and agility. J Int Soc Sports Nutr. 2015;12(Suppl 1):P41. doi:10.1186/1550-2783-12-S1-P41. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC4595381/
[10] Moreno MJ. Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther. 2003;25(1):178–193. doi:10.1016/S0149-2918(03)90023-3. Available at: https://pubmed.ncbi.nlm.nih.gov/12637119/
Pure Alpha GPC Success Stories
See how Pure Alpha GPC has helped othersand join our thriving community to experience the benefits firsthand