NMN supplements typically show noticeable effects, such as increased energy and focus, within a few days to weeks, while long-term benefits like improved metabolism and anti-aging effects may take months.
Alpha GPC as a Pre-Workout: Benefits, Dosage, and Safety
- Lifestyle
- April 2, 2025
- Gabriella J., partiQlar

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Key Takeaways:
- Alpha GPC enhances power output, focus, and endurance.
- Take 300-600 mg 30-60 minutes before your workouts.
- Avoid taking other choline-based supplements if you’re taking Alpha GPC.
Have you found yourself looking for alternatives to caffeine that enhances strength, focus, and endurance, but doesn’t come with unpleasant side effects? You may have come across a supplement called alpha GPC.
If you don’t understand what it is, don’t worry. We will explain everything. After reading this article, you’ll understand how it works and how it improves your workouts.

What Is Alpha GPC?
Alpha GPC (l-alpha-glycerylphosphorylcholine) is a powerful nootropic and sports performance enhancer. After consuming some, it crosses the blood-brain barrier and increases levels of the neurotransmitter acetylcholine, which is responsible for muscle contractions, learning, and memory.
Why does this matter for workouts? It’s quite simple: more acetylcholine results in improved cognitive function, sharper reaction times, and stronger muscle contractions. That’s the main reason why Alpha GPC is such a popular choice among athletes. It may boost their power output and mental focus in the gym.
How Alpha GPC Improves Workouts
You may think that the supplement is more about brain health, but it also directly improves athletic performance. In this section, you will find out how.
1. Increases Strength and Power
Studies show that Alpha GPC seems to enhance strength during workouts. However, it’s important to note that it won’t give you superhuman strength and focus. It’s been concluded that 6 days of supplementation resulted in greater than 3% increase in lower body isometric strength and peak force production in athletes (1).
Given that in most professional sports a very small change in performance (around ~2%) can affect the end result, the 3% that l-alpha-glycerylphosphorylcholine provides is why some coaches consider adding this supplementation to athlete’s regimens.
2. Enhances Focus and Reaction Time
Ever went for a workout and found yourself feeling mentally sluggish at the gym? If so, A-GPC could improve your mental focus and help you stay locked in on your workout.
Faster reaction times and better mind-muscle connection mean you’ll lift more efficiently and potentially avoid unnecessary injuries caused by lack of attention.
3. Reduces Fatigue
Alpha GPC may also support growth hormone secretion, which is responsible for muscle recovery and endurance. By delaying fatigue, it allows you to push through those last few reps and increase overload.
Studies suggest it increases the growth hormone response within 60 minutes of digestion, leading to better muscle repair and overall training performance (2).
How to Take Alpha GPC Before a Workout
If you feel like the supplement would benefit you and your workouts, you can buy Pure Alpha GPC at partiQlar’s to enjoy its advantages. Here are brief instructions on how to take it:
- Recommended dosage: 300-600 mg.
- Best time to take it: 30-60 minutes before exercise.
- Duration of effects: 4-6 hours.
- When effects begin: ~45 minutes after ingestion.
For more consistent results, make sure to take A-GPC daily, not just when you go out to train.
Alpha GPC vs Traditional Pre-Workouts
Most pre-workout supplements rely on caffeine for an energy boost and improved focus. However, there are some unpleasant side effects to caffeine that people complain about, such as jitters, crashes, and an elevated heart rate.
Alpha-glycerylphosphorylcholine, on the other hand, enhances mental focus and strength without overstimulating your nervous system. It’s a great choice if you want to get that extra motivation and energy without suffering caffeine’s downsides.
What NOT to Mix With Alpha GPC?
1. Caffeine: Should You Stack It or Avoid It?
Caffeine and Alpha GPC can be a strong combination for workouts. Caffeine increases adrenaline, while A-GPC sharpens focus and power output. But if you’re sensitive to caffeine, start with A-GPC alone before adding caffeine to the mix.
Also, keep in mind that it’s absolutely not necessary to mix anything if you’re an average gym-goer whose goal is to maintain health and grow some muscle.
2. Should It Be Taken With Food?
Alpha GPC is water-soluble, so you don’t need food for absorption. But if your stomach is sensitive and you’re afraid it might upset it if taken on an empty stomach, you can do it with a light meal.
3. Other Supplements to Avoid
Avoid stacking l-alpha-glycerylphosphorylcholine with other choline-based supplements like citicoline, as too much choline can lead to headaches or digestive issues
Why partiQlar’s Alpha GPC is the Best Choice?
Not all Alpha GPC supplements are created equal. PartiQlar’s Alpha GPC is:
- Pure and potent. No unnecessary fillers or additives.
- Third-party tested. Guaranteed purity and effectiveness.
- Clinically dosed. Optimized for performance without serious side effects.
Our product boasts the highest purity on the market (99%) and is sourced from Effepharm, which is a leader in science-backed ingredients. With us, you can always be sure that you get exactly what’s on the label. Nothing more, nothing less.
Conclusion
A-GPC is a great supplement for athletes who want to enhance strength, focus, and endurance. It increases your power output, improves cognitive function, and enhances your workout session.
All in all, it’s one of the best options available in the market that prevents cognitive decline during workouts, especially if you don’t want to take caffeine.
Frequently Asked Questions (FAQ)
Is Alpha GPC better than caffeine?
It depends. Alpha GPC enhances cognitive function and power output without the crash, while caffeine gives a short-term energy boost. Many athletes stack both for maximum performance. However, it’s absolutely unnecessary for regular gym-goers.
Can Alpha GPC burn fat?
A-GPC itself doesn’t burn fat, but by boosting workout performance, it can support muscle growth and metabolism, which indirectly helps with fat loss.
Can I take Alpha GPC with coffee?
Yes, many people take it with their morning coffee for enhanced focus. Just make sure you don’t overdose on caffeine to avoid overstimulation.
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