Pure Berberine HCL

(3 customer reviews)

$25.99$93.54 or subscribe and save 10%

Pure Berberine HCL capsules, each containing a potent 600 mg of pure Berberine Hydrochloride, free from any additives or fillers. Berberine is a natural alkaloid with a wide range of health benefits.

What is Berberine?

Berberine, an alkaloid found in plants like Goldenseal and Oregon grape, boasts a centuries-old history of medicinal use in China and India, primarily for combating infection and diarrhea. Modern science reveals its remarkable versatility and health benefits. Scroll down to explore all the benefits.


partiQlar Pure Berberine HCl capsules (vegan) contain Berberine Extract from Berberis Aristata (Bark) with the highest purity on the market — above 97%. Several scientific studies have investigated the bioavailability of berberine HCl, and results generally suggest that this form exhibits improved absorption compared to berberine alone. The enhanced bioavailability is a significant factor in the effectiveness of berberine. partiQlar Pure Berberine HCl is 3rd-party tested, sourced from a reliableand verified supplier, and produced in a USA FDA and NSF registered facility.


WHY partiQlar?

  • Purity
  • Source
  • Quality
  • 3d Party Testing
  • GMP Certifield Production Facilities
  • FDA Registered Production Facilities
  • Vegan

partiQlar Pure Berberine HCl

  • Highest purity in the market >97%
  • Verified suppliers
  • partiQlar and all involved partners stictly follows USP and FDA guidline to ensure 100% quality and safety.
  • 3d party lab tested.

Other Brands

  • Some with less than 80% purity
  • Unknown source
  • Questionable quality standards
  • No 3d party test
  • Purity
  • Source
  • Quality
  • 3d Party Testing
  • GMP Certifield Facilities
  • FDA Registered Facilities
  • Vegan

partiQlar Pure Resveratrol

  • Trans-resveratrol >99%
  • Effepharm
  • USP and FDA guideline
  • 3d party tested

Other Brands

  • Resveratrol <80% or lower
  • Unknown source
  • Weak quality standards
  • Not verifield

Blood Sugar Control

Berberine has demonstrated efficacy in regulating blood glucose levels by activating AMP-activated protein kinase (AMPK) pathways.

Cholesterol Management

Studies suggest that berberine can help lower cholesterol levels by inhibiting the enzyme PCSK9 and promoting the uptake of low-density lipoprotein (LDL) cholesterol.

Anti-Inflammatory Properties

Berberine exhibits anti-inflammatory effects through the modulation of various inflammatory pathways, including NF-κB and interleukin signaling.

Antimicrobial Effects

Berberine’s broad-spectrum antimicrobial properties make it effective against various infections, including bacteria, viruses, and fungi.

Weight Management

Berberine influences metabolism and adipogenesis, contributing to weight loss and the management of obesity-related conditions.

Neuroprotective Effects

Some studies suggest that berberine may have neuroprotective properties, potentially benefiting cognitive function and brain health.

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Scientific advisor

About Berberine HCl

Berberine in the hydrochloride (HCl) form has been studied for its potential to improve bioavailability. The addition of hydrochloride is believed to enhance the absorption of berberine in the gastrointestinal tract, addressing the challenge of berberine’s relatively low natural bioavailability. The hydrochloride salt form is often used to increase the solubility and stability of berberine, making it more readily absorbed by the body.

See what our customers have to say about

PartiQlar Pure Berberine HCL

3 reviews for Pure Berberine HCL

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    November 20, 2023
    Great product, fairly priced - fast delivery.
    Devin Anderson
    November 20, 2023
    I am taking these for high cholesterol..easy to swallow..
    November 20, 2023
    It helps maintain my blood sugar levels within the normal range; without it, I would be on the verge of diabetic levels. I consume one daily, and the pill's shape makes it easy to swallow. Additionally, I'm satisfied with its cost.
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Pure Berberine

– Check out our Science page, where we’ve written a detailed and easy-to-understand description of what Berberine.

– Berberine is an isoquinoline alkaloid (phytochemicals found in a number of plants) with a bright yellow color and bitter taste. It is commonly found in the root, rhizome, and stem bark of the Chinese herb Coptis chinensisand other Berberis plants. It has been used in traditional medicine for centuries, particularly in Chinese and Ayurvedic traditions.

– Yes, some studies suggest that berberine may have potential benefits for weight loss. Berberine has been investigated for its impact on various metabolic processes, including its ability to enhance insulin sensitivity, regulate blood sugar levels, and influence the metabolism of fats.

– Berberine exhibits various effects, including blood sugar regulation for improved insulin sensitivity, potential cholesterol management, implications for weight loss and metabolism regulation, anti-inflammatory properties, antimicrobial activity against bacteria, viruses, and fungi, and ongoing research into potential neuroprotective effects.

– Yes, Berberine has been found to have an anti-aging effect on skin. Berberine prevents TPA-induced ERK activation and AP-1 DNA binding activity, which can prevent skin inflammation and degradation of extracellular matrix proteins.

– No, on the contrary, according to some studies, Berberine can potentially lower estrogen.

– The appropriate dosage of berberine can vary depending on factors such as the specific health goal, individual health status, and the form of berberine used in the supplement. However, typical dosages used in clinical studies range from 500 mg to 1500 mg per day.

– Take berberine supplements with meals to minimize digestive discomfort and enhance absorption. If your daily dosage is higher, consider dividing it into two or three doses throughout the day for more stable levels. Aim for consistency by taking berberine at the same time each day

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