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GET TO KNOW
What is TMG?
TMG (Trimethylglycine) is frequently paired with NMN (Nicotinamide Mononucleotide) to enhance the benefits of increased NAD+ levels while maintaining healthy methylation. TMG acts as a methyl donor, providing essential methyl groups necessary for various physiological processes. While NMN boosts NAD+ levels, which are crucial for energy production, this process can deplete your body’s methyl stores.
By using TMG alongside NMN, you replenish these methyl groups, ensuring that NAD+ production remains efficient and balanced.
Homocysteine Levels
Human studies show that betaine effectively and reliably reduces homocysteine levels in both healthy individuals¹ and those with various conditions. Betaine can directly methylate homocysteine, offering potential cardioprotective benefits.
Cell Hydration
TMG also functions as an osmolyte, a molecule that moves in and out of cells to regulate their hydration status. Higher intracellular concentrations of TMG enhance cell hydration and resilience to stressors².
Methylation
TMG is a key natural methyl donor that supports methylation, a vital process for energy production, cell repair, and DNA synthesis. By donating its methyl group to convert the toxic metabolite homocysteine into methionine³, TMG helps maintain cellular health and function.
Physical Performance
Various studies suggest that TMG may enhance resistance exercise performance, particularly in endurance and high metabolic stress activities. It has shown potential to improve body composition, increase arm muscle size, boost barbell press capacity, and slightly enhance power (though not strength)⁴.
HOW TO TAKE
TMG Dosage
To Accompany NMN Supplementation – Well-known scientists who use TMG with NMN typically take 500 mg of TMG daily.
For Reducing Homocysteine Levels – for healthy individuals, a dose of 1.5–3 grams per day may be effective in managing homocysteine levels.
TMG is water-soluble and can be taken on with or without food. If you experience mild discomfort taking it on an empty stomach, consider having a healthy snack.
WHY partiQlar?
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Purity
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Source
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Quality
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3rd Party Testing
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GMP Certifield Production Facilities
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FDA Registered Production Facilities
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NON GMO
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Vegan
partiQlar Pure TMG
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500mg dosage
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Leading source supplier Effepharm
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Effepharm & partiQlar strictly follows USP and FDA guideline to ensure 100% quality
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Third-party tested for purity & label claim
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Other Brands
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Low dosage
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Unknown source
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Questionable quality standards
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No third-party test
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Purity
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Source
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Quality
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3rd Party Testing
-
GMP Certifield Facilities
-
FDA Registered Facilities
-
NON GMO
-
Vegan
partiQlar Pure TMG
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500mg dosage
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Effepharm
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USP and FDA guideline
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3rd party tested
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Other Brands
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Low dosage
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Unknown source
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Low quality standards
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Not verifield
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QUALITY
Facts
Highest Purity: partiQlar’s Pure TMG is free from unnecessary fillers and additives. Our formulation contains only pure, active ingredients for maximum potency.
Single-Ingredient Formulation: supported by scientific research, Pure TMG provides an effective 500 mg dosage of trimethylglycine (as betaine anhydrous), ensuring optimal flexibility.
Third-Party Tested: each batch undergoes rigorous third-party testing for purity and potency, ensuring transparency and reliability.
Sourced from a reputable and certified supplier, it is manufactured in a facility registered with the US FDA and NSF, adhering to stringent regulatory standards for safety and quality assurance.
We Want You to Ask Questions
PartiQlar’s Pure TMG offers unmatched quality with a high-purity, single-ingredient formulation free from unnecessary fillers and additives. Each capsule provides 500 mg of Trimethylglycine (as betaine anhydrous), ensuring maximum potency and flexibility. It is third-party tested for purity, potency, and safety, guaranteeing you receive the highest quality product.
PartiQlar’s Pure TMG offers unmatched quality with a high-purity, single-ingredient formulation free from unnecessary fillers and additives. Each capsule provides 500 mg of Trimethylglycine (as betaine anhydrous), ensuring maximum potency and flexibility. It is third-party tested for purity, potency, and safety, guaranteeing you receive the highest quality product.
Yes, TMG can help combat fatigue and increase energy by supporting cellular processes and reducing homocysteine levels. It also maintains optimal methylation, which is vital for energy production and reducing fatigue. Pairing TMG with NMN can further enhance energy and metabolic support.
Absolutely! TMG is often paired with NMN to enhance the benefits of increased NAD+ levels while maintaining healthy methylation. While NMN boosts NAD+ levels, TMG replenishes the methyl groups needed for various physiological processes, ensuring balanced and efficient cellular function.
For those supplementing with NMN, 500 mg of TMG daily is typically recommended. For managing homocysteine levels, a dose of 1.5–3 grams per day may be effective for healthy individuals. It’s best to start with a lower dose and gradually increase as needed, based on your specific health goals and response.
TMG is water-soluble and can be taken at any time of day, with or without food. If you experience mild discomfort taking it on an empty stomach, try taking it with a meal or snack. For best results, take TMG consistently at the same time each day.
No, TMG and creatine are distinct compounds with different functions. While both are osmolytes, TMG primarily supports methylation, liver function, and heart health, whereas creatine enhances energy production in muscle cells for improved athletic performance.
TMG is generally safe, but some people may experience mild digestive discomfort, such as nausea or bloating. If this occurs, take TMG with a healthy snack or meal. Starting with a lower dose can also help minimize potential side effects. Consult with a healthcare provider if discomfort persists.
More questions? Find answers on our FAQ page.
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4.5 out of 5.0 stars
Transparency you can trust. Discover what partiQlar users are saying.
TMG Supplement
Since starting TMG, I’ve noticed a steady improvement in my focus, and I can stay on task much longer than before.
Good
At first I didn’t know what is TMG useful for, but after using it 4 months, I feel more energized, more fit, more easy after my workouts
gracias
Trabaja al instante buen producto
Great after workout
I feel better rested, stronger after workouts, and generally healthier. I do heavy weight-lifting so recovery is the most important part for me. I can’t tell whether it’s because I was finally getting enough sleep, or because of glutathione, but it’s become a part of my daily routine, and I’m interested to see how things progress with long-term use.
TMG has been
TMG has been a surprising ally in my daily routine. I’m not sure how it works, but I feel more balanced and less prone to mood swings.
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Upgrade Your Longevity Routine
Elevate your wellness journey by pairing TMG with complementary supplements selected based on scientifically backed longevity protocols used by renowned experts. These recommendations are designed to optimize your routine and maximize your health benefits.
